ΕΠΑΓΓΕΛΜΑΤΙΚΗ ΕΜΠΕΙΡΙΑ

2018: Επίκουρος Καθηγητής Χειρουργικής Ιατρικής Σχολής ΕΚΠΑ - ΠΓΝ Αττικόν - Γ΄Πανεπιστημιακή Χειρουργική Κλινική

2018: Ακαδημαϊκός Υπότροφος Ιατρικής Σχολής ΕΚΠΑ - Αρεταίειο Νοσοκομείο, με γνωστικό αντικείμενο: Ελάχιστα Επεμβατική Χειρουργική Ενδοκρινών Αδένων

2015 - 2018 Ακαδημαϊκός Υπότροφος Ιατρικής Σχολής ΕΚΠΑ - Αρεταίειο Νοσοκομείο, με γνωστικό αντικείμενο: Προχωρημένη Λαπαροσκοπική Χειρουργική

ΕΚΠΑΙΔΕΥΣΗ

Εξειδικευση στη Χειρουργική Ενδοκρινών Αδένων

2013-2015          Εξειδίκευση στην Χειρουργική Ενδοκρινών Αδένων και Nευροενδοκρινικών Όγκων στο Hammersmith Hospital, Imperial College Healthcare NHS Trust και στο Royal Free Hospital του Λονδίνου.

Ειδικότητα Γενικής Χειρουργικής

2007-2013          Εκπαίδευση και λήψη τίλου εξειδίκευσης στην Ειδικότητα της Γενικής Χειρουργικής απο τη Β' Πανεπιστημιακή Χειρουργική κλινική του Εθνικού και Καπιδιστριακού Πανεπιστημίου Αθηνών.

Διδακτορική διατριβή

2006-2011          Διδάκτωρ Ιατρικής Σχολής Εθνικού και Καποδιστριακού Πανεπιστημίου Αθηνών, με θέμα «Διαταραχές της λειτουργίας του εντέρου σε πειραματικό μοντέλο ισχαιμίας και επαναιμάτωσης ήπατος χοίρων μετά ηπατεκτομή. Ο ρόλος του βιοτεχνητού ήπατος και της δεσφερριοξαμίνης».  Βαθμός Άριστα.

Ιατρική Σχολή

1999-2005          Πτυχίο Ιατρικής Σχολής του Εθνικού και              Καποδιστριακού Πανεπιστημίου Αθηνών, μετά από εισαγωγή με Πανελλήνιες Εξετάσεις, με βαθμό ‘Λίαν Καλώς’.

Δευτεροβάθμια Εκπαίδευση

1992-1998 Απόφοιτος Αμερικανικού Κολλεγίου Αθηνών Pierce

Μεταπτυχιακή Eκπαίδευση-Σεμινάρια:

2014

9th Multidisciplinary Symposium in Endocrinology and Endocrine Surgery. Imperial College Healthcare NHS Trust. Hammersmith Hospital. London, UK. 

2nd Combo Endocrinology Course In Neuroendocrine Tunors. Evangelistria Monasteri. Livadia, Greece.

International Post Graduate Course in Endocrine Surgery. Costa Navarino. Greece.

Course on Definite Trauma Surgical Care - DSTC Elpen Pharmakeuticals – Pikermi Athens

2013

8th Hammermsith Hospital Multidisciplinary Symposium. Hammersmith, London, UK

Hands-on National Training course on Thyroid ultrasound and FNAC for endocrinologists and Specialists in Thyroid disease. London, UK.

EASD Post-Graduate Course on the Current Treatment of Diabetes and its Complications. Instanbul, Turkey

Course on US and US-guided operative procedures for endocrine and thyroid Surgeons. Rome, Italy (BAETS 2013)

Hands-on Surgery Robotics Course for Consultants and Senior Registrars, UCH Education Centre for Robotics and Minimal Access Surgery. University College London Hospitals, London, UK.

Τhyroid and Parathyroid Master class Course, Royal College of Surgeons, London, UK.

Cerner Millennium Clinician’s Course, RoyalFreeHospital, London. UK.

Online course on “ENETS (European Neuroendocrine Tumor Society) guidelines for the management of well differentiated pancreatic NET”

E-AHPBA Postgraduate Course on HPB Surgery – “Management of Acute and Chronic Pancreatitis”. Royal College of Physicians, London, UK.

2012

7th HammermsithHospital Multidisciplinary Symposium. Hammersmith, London, UK

Hands-on course on Advanced Laparoscopic Surgery, Hellenic Surgical Society, ELPEN Experimental Surgical Unit, Athens, Greece. 

Post-graduate course on Colorectal surgery (Colorectal Games) and certificate of attendance after written exams Herakleion, Greece.                      

Certificate of attendance in Evidence Based Medicine Workshop in the European Digestive Surgery post-graduate Course.

Basic school of Hepatology “Hepatocyte Damage & Liver Metabolism” from the European Association for the Study of the Liver, Trieste, Italy.

Course on Advanced trauma Life Support-ATLS in MediterraneoHospital, Athens, Greece.

2010

Course on abdominal compartment syndrome. (Second prize after exams). 30th International Symposium on Intensive Care and Emergency Medicine Brussels, Belgium.

Laparoscopic course in General Surgery IRCAD-EITS, Strasburg, France.

Diplôme d'Université de Chirurgie Laparoscopique de Strasbourg

Postgraduate course in Hepatobiliary and Pancreatic Surgery, Greek Society of Hepatobiliary and pancreatic Surgery. Volos, Greece.  

ERC Course on Intermediate Life Support-ILS. Naval Hospital of Athens, Athens, Greece.

2009 

Course on Basic Laparoscopic Surgery from 2nd Department of Surgery Aretaieion University Hospital, Greece. (Prof. D. Voros - Course Coordinator Ass. Prof. G. Polymeneas)

Course on laparoscopic Surgery (Hands-on) from the University of Ioannina, Greece (Prof. Fatouros)

“Core skills in Laparoscopic Surgery” in Leeds, UK. (Prof. McMahon)

2008

ERC BLS/AED course (Basic life support), Naval Hospital of Athens, Athens, Greece

Δημοσιεύσεις σε Διεθνή Επιστημονικά Περιοδικά

1.            van der Pool A, Rawlings A, Sánchez-Guillén L, Kuiper S, Negoi I, Buchs N, et al. The impact of conversion on the risk of major complication following laparoscopic colonic surgery: an international, multicentre prospective audit. Colorectal Disease. 2018;20:69-89.

2.            Sánchez-Guillén L, Nepogodiev D, Sivrikoz E, van Elst T, Minaya A, Pata F, et al. Safety of primary anastomosis following emergency left sided colorectal resection: an international, multi-centre prospective audit. Colorectal Disease. 2018;20:47-57.

3.            Nastos K, Constantinides V, Mizamtsidi M, Duncan N, Tolley N, Palazzo F. Morbidity in parathyroid surgery for renal disease is under reported: A comparison of outcomes with primary hyperparathyroidism. Annals of the Royal College of Surgeons of England. 2018;100(6):436-42.

4.            Nastos C, Yiallourou A, Kotsis T, Mizamtsidi M, Delaportas D, Pafiti AK, et al. Immunohistochemical expression patterns of S100, synaptophysin, chromogranin A and neuron specific enolase in predicting malignant behaviour in paragangliomas. Journal of BUON. 2018;23(5):1540-5.

5.            Mouzakiti A, Nastos C, Vlachodimitropoulos D, Gennatas C, Kondi-Pafiti A, Voros D. Prognostic significance of EGFR and COX-2 expression in colorectal cancer and their association. A study in Greek population. Journal of BUON. 2018;23(1):23-8.

6.            Mizamtsidi M, Nastos C, Mastorakos G, Dina R, Vassiliou I, Gazouli M, et al. Diagnosis, management, histology and genetics of sporadic primary hyperparathyroidism: Old knowledge with new tricks. Endocrine Connections. 2018;7(2):R56-R68.

7.            Kotsis T, Nastos C, Stamatis K, Chondroudaki I, Pafiti A, Frangou M, et al. Insulin Metabolism and Assessment of Hepatic Insulin Extraction During Liver Regeneration. A Study in a Rat Model. Journal of Investigative Surgery. 2018:1-8.

8.            Kotsis T, Christoforou P, Nastos C, Chatziioannou A, Theodosopoulos T. Reversal of Acute Mesenteric Ischemia by Salvation of the Meandering Mesenteric Artery with Stenting of the Left Internal Iliac Artery. Annals of Vascular Surgery. 2018;46:370.e1-.e8.

9.            Glasbey JC, Blanco-Colino R, Kelly M, Singh B, Bhangu A, Pinkney T, et al. Association of mechanical bowel preparation with oral antibiotics and anastomotic leak following left sided colorectal resection: an international, multi-centre, prospective audit. Colorectal Disease. 2018;20:15-32.

10.          Giannoulopoulos D, Nastos C, Gavriatopoulou M, Vezakis A, Dellaportas D, Sotirova I, et al. The Role of TAMIS (Transanal Minimally Invasive Surgery) in the Management of Advanced Rectal Cancer – One Shared Story of Three Exceptional Cases. Journal of Investigative Surgery. 2018:1-6.

11.          Dellis AE, Skolarikos AA, Nastos K, Deliveliotis C, Varkarakis I, Mitsogiannis I, et al. The Impact of Technique Standardization on Total Operating and Fluoroscopy Times in Simple Endourological Procedures: A Prospective Study. Journal of Endourology. 2018;32(8):747-52.

12.          Bhangu A, Minaya-Bravo AM, Gallo G, Glasbey JC, Kamarajah S, Pinkney T, et al. An international multicentre prospective audit of elective rectal cancer surgery; operative approach versus outcome, including transanal total mesorectal excision (TaTME). Colorectal Disease. 2018;20:33-46.

13.          Battersby N, Glasbey JC, Neary P, Negoi I, Kamarajah S, Sgro A, et al. Evaluating the incidence of pathological complete response in current international rectal cancer practice: the barriers to widespread safe deferral of surgery. Colorectal Disease. 2018;20:58-68.

14.          Nastos K, Cheung VTF, Toumpanakis C, Navalkissoor S, Quigley AM, Caplin M, et al. Peptide Receptor Radionuclide Treatment and (131)I-MIBG in the management of patients with metastatic/progressive phaeochromocytomas and paragangliomas. Journal of Surgical Oncology. 2017;115(4):425-34.

15.          Dellis AE, Nastos K, Mastorakos D, Dellaportas D, Papatsoris A, Arkoumanis PT. Minimal surgical management of penile paraffinoma after subcutaneous penile paraffin injection. Arab Journal of Urology. 2017;15(4):387-90.

16.          Theodoraki K, Karmaniolou I, Tympa A, Tasoulis MK, Nastos C, Vassiliou I, et al. Beyond Preconditioning: Postconditioning as an Alternative Technique in the Prevention of Liver Ischemia-Reperfusion Injury. Oxidative medicine and cellular longevity. 2016;2016.

17.          Nastos C, Sotirova I, Papatsoris A, Skolarikos A, Papaconstantinou I, Dellis A. Unusual Case of Urethrorectal Fistula in Adolescence in a Patient with a History of Congenital Anorectal Malformation. Journal of endourology case reports. 2016;2(1):24-6.

18.          Nastos C, Kalimeris K, Papoutsidakis N, Defterevos G, Pafiti A, Kalogeropoulou E, et al. Bioartificial liver attenuates intestinal mucosa injury and gut barrier dysfunction after major hepatectomy: Study in a porcine model. Surgery (United States). 2016;159(6):1501-10.

19.          Mikrou A, Kalimeris KA, Lilis I, Papoutsidakis N, Nastos K, Papadaki H, et al. Molecular studies of the immunological effects of the sevoflurane preconditioning in the liver and lung in a rat model of liver ischemia/reperfusion injury. Molecular immunology. 2016;72:1-8.

20.          Defterevos G, Nastos C, Papalois A, Kalimeris K, Margelos V, Fragulidis G, et al. Peritoneal Albumin Dialysis as a Novel Approach for Liver Support: Study in a Porcine Model of Acute Hepatic Failure. Artificial organs. 2016.

21.          Athanasopoulos P, Mastoraki A, Papalois A, Nastos C, Kondi-Pafiti A, Kostopanagiotou G, et al. Expression of Inflammatory and Regenerative Genes in a Model of Liver Ischemia/Reperfusion and Partial Hepatectomy. Journal of Investigative Surgery. 2016;29(2):67-73.

22.          van Zaane B, van Klei WA, Buhre WF, Bauer P, Boerma EC, Hoeft A, et al. Nonelective surgery at night and in-hospital mortality: Prospective observational data from the European Surgical Outcomes Study. European journal of anaesthesiology. 2015;32(7):477-85.

23.          Trogadas G, Mastoraki A, Nastos C, Kondi-Pafiti A, Kostopanagiotou G, Smyrniotis V, et al. Comparative Effects of Ischemic Preconditioning and Iron Chelation in Hepatectomy. Journal of investigative surgery : the official journal of the Academy of Surgical Research. 2015;28(5):261-7.

24.          Lykoudis PM, Nastos C, Dellaportas D, Kairi-Vassilatou E, Dastamani C, Kondi-Pafiti A. Uncommon benign lesions of the adrenal glands mimicking sinister pathologies: Report of 8 cases. Journal of BUON. 2015;20(6):1630-4.

25.          Yiallourou AI, Ekonomou E, Tsamadias V, Nastos K, Karapanos K, Papaconstantinou I, et al. Association of Fokl and PvuII polymorphisms with breast cancer staging and survival among Caucasian women: A prospective study. Journal of BUON. 2014;19(3):633-42.

26.          Yiallourou AI, Ekonomou E, Tsamadias V, Nastos K, Karapanos K, Papaconstantinou I, et al. Association of FokI and PvuII polymorphisms with breast cancer staging and survival among Caucasian women: a prospective study. Journal of BUON : official journal of the Balkan Union of Oncology. 2014;19(3):633-42.

27.          Savvanis S, Nastos C, Tasoulis MK, Papoutsidakis N, Demonakou M, Karmaniolou I, et al. Sildenafil attenuates hepatocellular injury after liver ischemia reperfusion in rats: A preliminary study. Oxidative medicine and cellular longevity. 2014;2014.

28.          Papaconstantinou I, Zeglinas C, Gazouli M, Nastos K, Yiallourou A, Papalois A, et al. The Impact of Peri-operative Anti-TNF Treatment on Anastomosis-Related Complications in Crohn's Disease Patients. A Critical Review. Journal of Gastrointestinal Surgery. 2014;18(6):1216-24.

29.          Papaconstantinou I, Zeglinas C, Gazouli M, Nastos K, Yiallourou A, Lykoudis P, et al. Effect of infliximab on the healing of intestinal anastomosis: An experimental study in rats. International Journal of Surgery. 2014;12(9):969-75.

30.          Nastos C, Vezakis A, Papaconstantinou I, Theodosopoulos T, Koutoulidis V, Polymeneas G. Methods of safe laparoscopic cholecystectomy for left-sided (sinistroposition) gallbladder: A report of two cases and a review of safe techniques. International journal of surgery case reports. 2014;5(10):769-73.

31.          Nastos C, Kalimeris K, Papoutsidakis N, Tasoulis MK, Lykoudis PM, Theodoraki K, et al. Global consequences of liver ischemia/reperfusion injury. Oxidative medicine and cellular longevity. 2014;2014.

32.          Lykoudis PM, O'Reilly D, Nastos K, Fusai G. Systematic review of surgical management of synchronous colorectal liver metastases. British Journal of Surgery. 2014;101(6):605-12.

33.          Karakatsanis A, Lykoudis P, Nastos C, Chronopoulos E, Koutoulidis V, Polymeneas G, et al. Bilateral obturator pyomyositis with visceral involvement in an immunocompetent adult patient treated without surgery. Surgical infections. 2014;15(5):651-5.

34.          Vassiliou I, Tympa A, Theodosopoulos T, Nastos C, Arkadopoulos N, Dafnios N, et al. Erratum: Late Polypropylene Mesh Susceptibility to Infection During Intra-Abdominal Sepsis (Journal of Investigative Surgery (2011) 24:5 (199-204)). Journal of Investigative Surgery. 2013;26(3):165.

35.          Varsos P, Nastos C, Papoutsidakis N, Kalimeris K, Defterevos G, Nomikos T, et al. Desferrioxamine attenuates pancreatic injury after major hepatectomy under vascular control of the liver: Experimental study in pigs. HPB Surgery. 2012;2012.

36.          Theodoraki K, Arkadopoulos N, Nastos C, Vassiliou I, Karmaniolou I, Smyrniotis V. Small liver remnants are more vulnerable to ischemia/reperfusion injury after extended hepatectomies: A case-control study. World Journal of Surgery. 2012;36(12):2895-900.

37.          Pearse RM, Moreno RP, Bauer P, Pelosi P, Metnitz P, Spies C, et al. Mortality after surgery in Europe: A 7 day cohort study. The Lancet. 2012;380(9847):1059-65.

38.          Pearse RM, Moreno RP, Bauer P, Pelosi P, Metnitz P, Spies C, et al. Mortality after surgery in Europe: a 7 day cohort study. Lancet (London, England). 2012;380(9847):1059-65.

39.          Arkadopoulos N, Nastos C, Defterevos G, Kalimeris K, Papoutsidakis N, Andreadou I, et al. Pancreatic injury after major hepatectomy: A study in a porcine model. Surgery today. 2012;42(4):368-75.

40.          Vezakis A, Fragulidis G, Nastos C, Yiallourou A, Polydorou A, Voros D. Closure of a persistent sphincterotomy-related duodenal perforation by placement of a covered self-expandable metallic biliary stent. World journal of gastroenterology. 2011;17(40):4539-41.

41.          Vezakis A, Fragulidis G, Nastos C, Yallourou A, Polydorou A, Voros D. Closure of a persistent sphincterotomy-related duodenal perforation by placement of a covered self-expandable metallic biliary stent. World journal of gastroenterology. 2011;17(40):4539-41.

42.          Vassiliou I, Tympa A, Theodosopoulos T, Nastos C, Arkadopoulos N, Dafnios N, et al. Late polypropylene mesh susceptibility to infection during intra-abdominal sepsis. Journal of investigative surgery : the official journal of the Academy of Surgical Research. 2011;24(5):199-204.

43.          Tympa A, Nastos C, Defterevos G, Papalois A, Kalimeris K, Kostopanagiotou G, et al. Effects of intraperitoneal albumin on systemic and cerebral hemodynamics in a swine model of acute liver failure. Journal of Investigative Surgery. 2011;24(3):129-33.

44.          Papoutsidakis N, Arkadopoulos N, Smyrniotis V, Tzanatos H, Kalimeris K, Nastos K, et al. Early myocardial injury is an integral component of experimental acute liver failure - A study in two porcine models. Archives of Medical Science. 2011;7(2):217-23.

45.          Nastos C, Kalimeris K, Papoutsidakis N, Defterevos G, Pafiti A, Kalogeropoulou H, et al. Antioxidant Treatment Attenuates Intestinal Mucosal Damage and Gut Barrier Dysfunction After Major Hepatectomy. Study in a Porcine Model. Journal of Gastrointestinal Surgery. 2011;15(5):809-17.

46.          Fragulidis GP, Athanasopoulos PG, Melemeni A, Chondrogiannis KD, Nastos K, Koutoulidis V, et al. Pylorus-preserving pancreaticoduodenectomy after transhiatal esophagectomy sparing the right gastroepiploic vessels and gastric tube. Journal of Gastrointestinal Surgery. 2011;15(2):367-70.

47.          Dellaportas D, Nastos C, Psychogiou V, Tympa A, Tsaroucha A, Kontis J, et al. Iatrogenic liver trauma managed with mesh-wrapping and ligation of portal vein branch: A case report. International journal of surgery case reports. 2011;2(8):261-3.

48.          Arkadopoulos N, Kostopanagiotou G, Nastos C, Papalois A, Papoutsidakis N, Kalimeris K, et al. Reversal of Experimental Posthepatectomy Liver Failure in Pigs: A New Application of Hepatocyte Bioreactors. Artificial organs. 2011;35(1):29-36.

49.          Arkadopoulos N, Defterevos G, Nastos C, Papalois A, Kalimeris K, Papoutsidakis N, et al. Development of a porcine model of post-hepatectomy liver failure. Journal of Surgical Research. 2011;170(2):e233-e42.

50.          Vassiliou I, Lolis E, Nastos C, Tympa A, Theodosopoulos T, Dafnios N, et al. The combined effect of erythropoietin and granulocyte macrophage colony stimulating factor on liver regeneration after major hepatectomy in rats. World journal of surgical oncology. 2010;8.

51.          Skalkidis Y, Nastos C, Zavitsianos X. Clinical protocols and clinical guidelines: Issues related to their applicability in everyday clinical practice. Archives of Hellenic Medicine. 2010;27(2):264-73.

52.          Skalkidis Y, Nastos C, Zavitsanos X. Clinical protocols and clinical guidelines: Issues related to their applicability in everyday clinical practice. Archives of Hellenic Medicine. 2010;27(2):264-73.

53.          Kostopanagiotou G, Kalimeris K, Christodoulaki K, Nastos C, Papoutsidakis N, Dima C, et al. The differential impact of volatile and intravenous anaesthetics on stress response in the swine. Hormones. 2010;9(1):67-75.

54.          Kalimeris K, Nastos C, Papoutsidakis N, Xanthopoulou MN, Defterevos G, Tympa A, et al. Iron chelation prevents lung injury after major hepatectomy. Hepatology Research. 2010;40(8):841-50.

55.          Dellaportas D, Tympa A, Nastos C, Psychogiou V, Karakatsanis A, Polydorou A, et al. An ongoing dispute in the management of severe pancreatic fistula: Pancreatospleenectomy or not? World journal of gastrointestinal surgery. 2010;2(11):381-4.

56.          Arkadopoulos N, Nastos C, Kalimeris K, Economou E, Theodoraki K, Kouskouni E, et al. Iron chelation for amelioration of liver ischemia-reperfusion injury. Hemoglobin. 2010;34(3):265-77.

57.          Arkadopoulos N, Kalimeris K, Papalois A, Nastos C, Papoutsidakis N, Defterevos G, et al. Treatment with bioartificial liver improves lung injury in a swine model of partial hepatectomy and ischemia/reperfusion. International Journal of Artificial Organs. 2010;33(2):105-13.

Βραβεία και Διακρίσεις

Βραβείο καλύτερης προφορικής ανακοίνωσης στο 2ο Επιστημονικό συνέδριο των Φοιτητών Ιατρικής Ελλάδας  

(Development of a experimental model of post-operative liver failure and liver support with bioartificial liver).

Βραβείο καλύτερης προφορικής ανακοίνωσης στο 10ο συνέδριο αναισθησιολογίας και εντατικής θεραπείας

(The effect of bioartificial liver in lung injury following hepatectomy)

Βραβείο καλύτερης προφορικής ανακοίνωσης στο 6ο Πανελλήνιο παγκρεατολογικό συνέδριο  

(Study of pancreatic function after major hepatectomy and post-operative liver support with bioartificial liver in a porcine model)

Βραβείο καλύτερης αναρτημένης ανακοίνωσης στο 26ο Πανελλήνιο Χειρουργικό Συνέδριο

(Attenuation of intestinal mucosa damage following major hepatectomy with desferrioxamine).

Βραβείο καλύτερης προφορικής ανακοίνωσης στο 32ο Πανελλήνιο Γαστρεντερολογικό Συνέδριο 

(The effect of anti-TNF treatment in the healing of enteral anastomosis).

Βραβείο αναρτημένης ανακοίνωσης στο συνέδριο νευροενδοκρινών όγκων του Ηνωμένου Βασιλείου UKI-NETS.

(Comparison of radiolableled somatostatin analogues and (131) I-MIBG treatment for the management of patients with metastatic/progressive Phaeochromocytomas and Paragangliomas.)